**D-2-Aminobutyric Acid (D-Abu-OH)**
Also known as: D(-)-2-aminobutyric acid, Da-aminobutyric acid, (R)-2-aminobutyric acid, D-Aminobutyric acid amide.
**Chemical Name:** D-2-Aminobutyric Acid
**CAS Number:** 2623-91-8
**Molecular Formula:** C₄H₉NO₂
**Molecular Weight:** 103.12 g/mol
**Purity:** ≥99.0%
**Ash Content:** ≤0.10%
**Appearance:** White crystalline powder or colorless flaky crystals
**Melting Point:** ≥300°C
**Specific Optical Rotation:** +7.94 (c=4 in Hâ‚‚O)
**Applications:**
This compound is widely used in biochemical research, particularly in the development and validation of ELISA kits for various biomarkers. It serves as a key reagent in assays related to human lactate dehydrogenase (LDH), apoptosis inhibitors (IAP), sugar-deficient transferrin (CDT), ubiquitin-conjugating enzymes (E2/UBCE), and more. It is also utilized in immunoassays for mouse gastrointestinal cancer markers (CA199), interleukin-1 soluble receptor I (IL-1sRI), α-L-fucosidase (AFU), porcine gastrin receptor (GsaR), and other proteins involved in immune and metabolic pathways.
**Storage:**
Store at room temperature (RT).
**ELISA Applications Overview:**
- **Human LDH (Lactate Dehydrogenase):** Used in diagnostic assays to detect tissue damage.
- **Human IAP (Inhibitor of Apoptosis):** Involved in cell survival and resistance to apoptosis.
- **Human CDT (Sugar-Deficient Transferrin):** A biomarker for alcohol abuse.
- **Human E2/UBCE (Ubiquitin-Conjugating Enzyme):** Plays a role in protein degradation.
- **Mouse IL-1sRI (Interleukin-1 Soluble Receptor I):** Involved in inflammatory responses.
- **Mouse AFU (α-L-Fucosidase):** Related to lysosomal storage disorders.
- **Porcine GsaR (Gastrin Receptor):** Important in gastric function and tumor studies.
- **Porcine SP-A (Surfactant Protein A):** Critical for lung surfactant function.
- **Human ET-1 (Endothelin-1):** A potent vasoconstrictor involved in cardiovascular diseases.
- **Human AmAC-1 (Macrophage Activation-Related Chemokine 1):** Involved in immune response regulation.
This high-purity compound is essential for accurate and reliable ELISA results, making it a valuable tool in both academic and clinical research settings.
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