Interleukin-6,10,12,13

Interleukin-6, also known as IL-6, is a cytokine primarily produced by activated monocytes, fibroblasts, and endothelial cells. It plays a crucial role in immune responses by stimulating the proliferation of T cells, B cells, and hybridoma cells. IL-6 enhances immunoglobulin production by B cells, promotes the differentiation of cytotoxic T cells and megakaryocytes, and induces the synthesis of acute-phase reactive proteins. Its influence extends to the nervous, endocrine, and hematopoietic systems, making it a key player in both inflammatory and regulatory processes. Interleukin-10 (IL-10) is another important cytokine, mainly derived from Th2 cells and regulatory T cells. It functions as an anti-inflammatory agent by suppressing Th1 cell activity and inhibiting macrophage antigen presentation and cytokine production. At the same time, IL-10 supports B cell proliferation, differentiation, and antibody production, contributing to immune balance. Interleukin-12 (IL-12), also called NK cell stimulatory factor (NKSF), is composed of two subunits, p40 and p35, which are structurally related to the IL-6 receptor alpha chain. This cytokine is essential for activating natural killer (NK) cells and promoting the differentiation of CD4+ Th0 cells into Th1 cells. It works synergistically with low doses of IL-2 to enhance LAK cell activity, playing a vital role in cell-mediated immunity. Interleukin-13 (IL-13) is secreted by activated T cells and has diverse effects on the immune system. It stimulates B cell proliferation and differentiation, facilitates immunoglobulin class switching, and supports monocyte survival and differentiation. Additionally, IL-13 suppresses the activity and cytokine production of mononuclear/macrophage cells, highlighting its regulatory function in inflammation. In addition to these cytokines, there are numerous reference standards available for various compounds, including: - 4-[2-(5-methylpyrazine-2-carboxamido-)ethyl]-sulfonamide - Citrate standard - Trimebutine maleate - Berberine II - Oxazolone - Pyrazinamide - L-shikonin - Melphalan - Chuanxi Zhang (a traditional herb) - Ganmutong - Ranitidine - Citrulline - Fenugreek hydrochloride - Fluphenazine hydrochloride - Low molecular weight protein standard (SDS method) - Shikonin alcohol - Kushen - Estradiol - Serine - Ofloxacin Impurity B - Deacyl glucoside aglycone - Rimantadine hydrochloride - Mitoxantrone hydrochloride - Dispersing yellow 3 - Qingyangshen aglycone - Cefaclor - Cefaclor δ-3 isomer - 7-Amino-desacetoxycephalosporanic acid (7-ADCA) - Wood-Phenyl Glycoside B - Pingentinolate - Phellodamine - Xibei mother base - Hydrochloric acid dechlorin - Dongfeng orange - Schisandra A - 2,3,3-trichlorobiphenyl - Grass standard - Chlorzoxazone - Bacterium - Hydrogenated cortisone acetate - Isolated isoeugenol - Ortho-cresol - Etidronate disodium - pH standard - Huang Caulinu - Ge grass net - Spinoquinone B - Methanol - Turmeric - Lotus base - Domingo - Flying Grass - Chlorfenone - Cryptotanshinone - Turtle toxin - Acetic acid Ruilin - Xiang Zhi - Ammonia toluic acid - Ginseng - Amika star impurity A - Niacin - Cerium solution - Zinc citrate - Hydroxy citric acid - n-Butanol - Lotus seed - Sand glucose agar - Benzidine - Forsythia - Ezetine B acetate - Lead solution - Isochlorogenic acid A - Original hundred base - Tacrolimus - Cactus - Ginsenoside Rg3 - Allicin - Thorn pear - Normethrin lactone - Rosmarinic acid - Isopropyl antipyrine - Vincristine - Cholesterol - Arbutin - Atenolol - Erlenitin - Deoxynojirimycin - Patchouli - Caffeic acid - EPA halogenated volatile mix - Enethrin These reference standards are essential for quality control, research, and analytical testing in pharmaceutical and biochemical fields. They ensure accurate and reliable results in drug development, clinical studies, and environmental monitoring.

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