Some experiences when using liquid chromatography-mass spectrometry system for the analysis of small molecule compounds

Because of its high sensitivity to most compounds, liquid-mass spectrometry is more and more widely used. It is suitable for qualitative and quantitative analysis of in vivo drugs, toxic substances in the body, and impurities in drugs. Compared with the analysis methods of traditional chromatographic separation detectors (UV, fluorescence, parallax, evaporative light scattering, electrochemistry, etc.), mass spectrometry belongs to the broad suitability detector of liquid chromatography, and has obvious advantages. Wide, sensitive and high-throughput characteristics, it can meet the qualitative and quantitative requirements of multiple fields.

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